Src and ROCK Kinases Differentially Regulate Mineralization of Human Osteosarcoma Saos-2 Cells

Src and ROCK Kinases Differentially Regulate Mineralization of Human Osteosarcoma Saos-2 Cells

Osteoblasts initiate bone mineralization by releasing matrix vesicles (MVs) into the extracellular matrix (ECM). MVs promote the nucleation process of apatite formation from Ca<sup>2+</sup> and P<sub>i</sub> in their lumen and bud from the microvilli of osteoblasts during bon...

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Bibliographic Details
Main Authors: Agnieszka Strzelecka-Kiliszek, Marta Romiszewska, Lukasz Bozycki, Saida Mebarek, Joanna Bandorowicz-Pikula, Rene Buchet, Slawomir Pikula
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:International Journal of Molecular Sciences
Subjects:
Src kinase
ROCK
annexin A6
mineralization
matrix vesicles
Saos-2 cells
Online Access:https://www.mdpi.com/1422-0067/20/12/2872

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