Therapeutic impact of Human serum albumin-thioredoxin fusion protein on influenza virus-induced lung injury mice

Therapeutic impact of Human serum albumin-thioredoxin fusion protein on influenza virus-induced lung injury mice

Reactive oxygen species (ROS) are the primary pathogenic molecules produced in viral lung infections. We previously reported on the use of a recombinant human serum albumin (HSA)-thioredoxin 1 (Trx) fusion protein (HSA-Trx) for extending the half-life Trx, an endogenous protein with antioxidant prop...

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Bibliographic Details
Main Authors: Ryota eTanaka, Yu eIshima, Yuki eEnoki, Kazuhiko eKimachi, Tatsuya eShirai, Hiroshi eWatanabe, Victor T. G. eChuang, Toru eMaruyama, Masaki eOtagiri
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-11-01
Series:Frontiers in Immunology
Subjects:
Fusion
thioredoxin
albumin
Anti-oxidization
Influenza virus.
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00561/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00561/full

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