Landscape of Non-canonical Cysteines in Human VH Repertoire Revealed by Immunogenetic Analysis

Summary: Human antibody repertoire data captured through next-generation sequencing (NGS) has enabled deeper insights into B cell immunogenetics and paratope diversity. By analyzing large public NGS datasets, we map the landscape of non-canonical cysteines in human variable heavy-chain domains (VHs)...

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Bibliographic Details
Main Authors: Ponraj Prabakaran, Partha S. Chowdhury
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720308123

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