Fast MCMC sampling for hidden markov models to determine copy number variations

<p>Abstract</p> <p>Background</p> <p>Hidden Markov Models (HMM) are often used for analyzing Comparative Genomic Hybridization (CGH) data to identify chromosomal aberrations or copy number variations by segmenting observation sequences. For efficiency reasons the parame...

Full description

Bibliographic Details
Main Authors: Mahmud Md Pavel, Schliep Alexander
Format: Article
Language:English
Published: BMC 2011-11-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/12/428