Potential Role of Induced Pluripotent Stem Cells (IPSCs) for Cell-Based Therapy of the Ocular Surface

Potential Role of Induced Pluripotent Stem Cells (IPSCs) for Cell-Based Therapy of the Ocular Surface

The integrity and normal function of the corneal epithelium are crucial for maintaining the cornea’s transparency and vision. The existence of a cell population with progenitor characteristics in the limbus maintains a dynamic of constant epithelial repair and renewal. Currently, cell-based therapie...

Full description

Bibliographic Details
Main Authors:	Ricardo P. Casaroli-Marano, Núria Nieto-Nicolau, Eva M. Martínez-Conesa, Michael Edel, Ana B.Álvarez-Palomo
Format:	Article
Language:	English
Published:	MDPI AG 2015-02-01
Series:	Journal of Clinical Medicine
Subjects:	limbal stem cells cornea limbal stem cell deficiency epithelial differentiation human adult progenitor cells ex vivo expansion cell culture ocular burns cell-based therapy human stem cells
Online Access:	http://www.mdpi.com/2077-0383/4/2/318

Similar Items

Goals and Challenges of Stem Cell-Based Therapy for Corneal Blindness Due to Limbal Deficiency
by: Margarita Calonge, et al.
Published: (2021-09-01)

Conjunctival-limbal autograft in total unilateral limbal stem cell deficiency
by: Petra Schollmayer, et al.
Published: (2017-09-01)

Ocular Surface Reconstruction with Cultivated Limbal Epithelial Cells in Limbal Stem Cell Deficiency: One-year Follow-up Results
by: İsmet Durak, et al.
Published: (2012-05-01)

Combined autologous and allograft limbal cell transplantation with penetrating keratoplasty in a case of chemical corneal burn patient
by: Sandip Mitra
Published: (2009-01-01)

Simple limbal epithelial transplantation: Current status and future perspectives
by: Catherine J. Jackson, et al.
Published: (2020-03-01)

EFFICIENCY OF AMNIOTIC MEMBRANE TRANSPLANTATION IN THE MANAGEMENT OF LIMBAL STEM CELL DEFICIENCY
by: Vitalie Procopciuc, et al.
Published: (2020-10-01)

Current perspectives of limbal‐derived stem cells and its application in ocular surface regeneration and limbal stem cell transplantation
by: Vivek Singh, et al.
Published: (2021-08-01)

Mini-Review: Regenerating the Corneal Epithelium With Simple Limbal Epithelial Transplantation
by: Aastha Singh, et al.
Published: (2021-05-01)

Efficacy of Modified Amnion-Assisted Conjunctival Epithelial Redirection (ACER) for Partial Limbal Stem Cell Deficiency
by: Sang Beom Han, et al.
Published: (2021-04-01)

Stem Cell Niche Microenvironment: Review
by: Abdul-Al, Mohamed, et al.
Published: (2021)

Simple limbal epithelial transplantation (SLET): Review of indications, surgical technique, mechanism, outcomes, limitations, and impact
by: Swapna S Shanbhag, et al.
Published: (2019-01-01)

Мodification of Mechanical Limbal Stem Cell Deficiency Model
by: A. V. Bezushko, et al.
Published: (2018-03-01)

Limbal stem cell deficiency: etiology, pathogenesis, priniciples and prospects of surgical treatment
by: A. S. Dubovikov, et al.
Published: (2019-03-01)

Primary limbal stem cell transplantation in the surgical management of extensive ocular surface squamous neoplasia involving the limbus
by: Purvasha Narang, et al.
Published: (2018-01-01)

Lineage tracing in the adult mouse corneal epithelium supports the limbal epithelial stem cell hypothesis with intermittent periods of stem cell quiescence
by: Natalie J. Dorà, et al.
Published: (2015-11-01)

Quantification of corneal neovascularization after ex vivo limbal epithelial stem cell therapy
by: Adriano Guarnieri, et al.
Published: (2014-12-01)

Current and Emerging Therapies for Limbal Stem Cell Deficiency
by: Djalilian, A.R, et al.
Published: (2022)

Conjunctival limbal autografting (CLAU) combined with customised simple limbal epithelial transplantation (SLET) in a severe corneal chemical burn: Case report
by: Christophe Panthier, et al.
Published: (2020-12-01)

Subconjunctival injection of mesenchymal stem cells for corneal failure due to limbal stem cell deficiency: state of the art
by: Sara Galindo, et al.
Published: (2021-01-01)

Preliminary results from the comparison of simple limbal epithelial transplantation with conjunctival limbal autologous transplantation in severe unilateral chronic ocular burns
by: Ritu Arora, et al.
Published: (2017-01-01)

Limbal Stem Cell Deficiency and Treatment with Stem Cell Transplantation
by: Özlem Barut Selver, et al.
Published: (2017-12-01)

Clinical outcomes of modified simple limbal epithelial transplantation for limbal stem cell deficiency in Chinese population: a retrospective case series
by: Yinghui Wang, et al.
Published: (2021-05-01)

Autologous limbal stem cell transplantation for limbus papilloma treatment
by: Er-Juan Xie, et al.
Published: (2016-03-01)

Early Results of Penetrating Keratoplasty following Limbal Stem Cell Transplantation
by: Sangwan Virender, et al.
Published: (2005-03-01)

Human Umbilical Cord-Derived Mesenchymal Stem Cells Promote Corneal Epithelial Repair In Vitro
by: Santhosh Kacham, et al.
Published: (2021-05-01)

Propagation of limbal stem cells on polycaprolactone and polycaprolactone/gelatin fibrous scaffolds and transplantation in animal model
by: Fatemeh Sanie-Jahromi, et al.
Published: (2020-01-01)

Derivation and Characterization of EGFP-Labeled Rabbit Limbal Mesenchymal Stem Cells and Their Potential for Research in Regenerative Ophthalmology
by: Julia I. Khorolskaya, et al.
Published: (2021-09-01)

A 3D culture system enhances the ability of human bone marrow stromal cells to support the growth of limbal stem/progenitor cells
by: Sheyla González, et al.
Published: (2016-03-01)

Recent Advances in Stem Cell Therapy for Limbal Stem Cell Deficiency: A Narrative Review
by: Ali E. Ghareeb, et al.
Published: (2020-09-01)

Xenofree generation of limbal stem cells for ocular surface advanced cell therapy
by: Nuria Nieto-Nicolau, et al.
Published: (2019-12-01)

Xeno- and feeder-free differentiation of human pluripotent stem cells to two distinct ocular epithelial cell types using simple modifications of one method
by: Heidi Hongisto, et al.
Published: (2017-12-01)

Experimental study on decompensation model of rabbit corneal limbal stem cells induced by alkali burn
by: Qing-Qin Gao, et al.
Published: (2019-05-01)

Induced pluripotent stem cells as a potential therapeutic source for corneal epithelial stem cells
by: Jie Zhu, et al.
Published: (2018-12-01)

Extracellular Matrix is an Important Component of Limbal Stem Cell Niche
by: Sophie X. Deng, et al.
Published: (2012-12-01)

Results of simple limbal epithelial transplantation in unilateral ocular surface burn
by: Nidhi Gupta, et al.
Published: (2018-01-01)

Efficient Isolation and Expansion of Limbal Melanocytes for Tissue Engineering
by: Polisetti, N., et al.
Published: (2023)

Transcriptome Analysis of Cultured Limbal Epithelial Cells on an Intact Amniotic Membrane following Hypothermic Storage in Optisol-GS
by: Tor Paaske Utheim, et al.
Published: (2016-02-01)

Sleep deprivation induces corneal epithelial progenitor cell over-expansion through disruption of redox homeostasis in the tear film
by: Anchouche, S., et al.
Published: (2022)

Rat limbal niche cells can induce transdifferentiation of oral mucosal epithelial cells into corneal epithelial-like cells in vitro
by: Xin-Yue Zhao, et al.
Published: (2018-09-01)

Corneal epithelial healing in rabbit eyes with partial corneal-conjunctival and conjunctival limbal deficiency
by: Diane Ruschel Marinho, et al.