Biological Activity of Quaternary Ammonium Salts and Their Derivatives

Besides their positive role, microorganisms are related to a number of undesirable effects, including many diseases, biodeterioration and food spoilage, so when their presence is undesired, they must be controlled. Numerous biocides limiting the development of microorganisms have been proposed, howe...

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Main Authors: Dobrawa Kwaśniewska, Ying-Lien Chen, Daria Wieczorek
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Pathogens
Subjects:
Online Access:https://www.mdpi.com/2076-0817/9/6/459
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spelling doaj-d05f9b27670e463096748f0e352aa04b2020-11-25T03:20:38ZengMDPI AGPathogens2076-08172020-06-01945945910.3390/pathogens9060459Biological Activity of Quaternary Ammonium Salts and Their DerivativesDobrawa Kwaśniewska0Ying-Lien Chen1Daria Wieczorek2Department of Technology and Instrumental Analysis, Institute of Quality Science, Poznań University of Economics and Business, 61-875 Poznań, PolandDepartment of Plant Pathology and Microbiology, National Taiwan University, Taipei 10617, TaiwanDepartment of Technology and Instrumental Analysis, Institute of Quality Science, Poznań University of Economics and Business, 61-875 Poznań, PolandBesides their positive role, microorganisms are related to a number of undesirable effects, including many diseases, biodeterioration and food spoilage, so when their presence is undesired, they must be controlled. Numerous biocides limiting the development of microorganisms have been proposed, however, in this paper the biocidal and inhibitory activity of quaternary ammonium salts (QASs) and their zwitterionic derivatives is addressed. This paper presents the current state of knowledge about the biocidal activity of QAS and their derivatives. Moreover, the known mechanisms of antimicrobial activity and the problem of emerging resistance to QAS are discussed. The latest trends in the study of surfactants and their potential use are also presented.https://www.mdpi.com/2076-0817/9/6/459quaternary ammonium saltssulfobetainesbiocidal activity
collection DOAJ
language English
format Article
sources DOAJ
author Dobrawa Kwaśniewska
Ying-Lien Chen
Daria Wieczorek
spellingShingle Dobrawa Kwaśniewska
Ying-Lien Chen
Daria Wieczorek
Biological Activity of Quaternary Ammonium Salts and Their Derivatives
Pathogens
quaternary ammonium salts
sulfobetaines
biocidal activity
author_facet Dobrawa Kwaśniewska
Ying-Lien Chen
Daria Wieczorek
author_sort Dobrawa Kwaśniewska
title Biological Activity of Quaternary Ammonium Salts and Their Derivatives
title_short Biological Activity of Quaternary Ammonium Salts and Their Derivatives
title_full Biological Activity of Quaternary Ammonium Salts and Their Derivatives
title_fullStr Biological Activity of Quaternary Ammonium Salts and Their Derivatives
title_full_unstemmed Biological Activity of Quaternary Ammonium Salts and Their Derivatives
title_sort biological activity of quaternary ammonium salts and their derivatives
publisher MDPI AG
series Pathogens
issn 2076-0817
publishDate 2020-06-01
description Besides their positive role, microorganisms are related to a number of undesirable effects, including many diseases, biodeterioration and food spoilage, so when their presence is undesired, they must be controlled. Numerous biocides limiting the development of microorganisms have been proposed, however, in this paper the biocidal and inhibitory activity of quaternary ammonium salts (QASs) and their zwitterionic derivatives is addressed. This paper presents the current state of knowledge about the biocidal activity of QAS and their derivatives. Moreover, the known mechanisms of antimicrobial activity and the problem of emerging resistance to QAS are discussed. The latest trends in the study of surfactants and their potential use are also presented.
topic quaternary ammonium salts
sulfobetaines
biocidal activity
url https://www.mdpi.com/2076-0817/9/6/459
work_keys_str_mv AT dobrawakwasniewska biologicalactivityofquaternaryammoniumsaltsandtheirderivatives
AT yinglienchen biologicalactivityofquaternaryammoniumsaltsandtheirderivatives
AT dariawieczorek biologicalactivityofquaternaryammoniumsaltsandtheirderivatives
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