Self-crosslinkable chitosan-hyaluronic acid dialdehyde nanoparticles for CD44-targeted siRNA delivery to treat bladder cancer

Self-crosslinkable chitosan-hyaluronic acid dialdehyde nanoparticles for CD44-targeted siRNA delivery to treat bladder cancer

Bladder cancer is one of the concerning malignancies worldwide, which is lacking effective targeted therapy. Gene therapy is a potential approach for bladder cancer treatment. While, a safe and effective targeted gene delivery system is urgently needed for prompting the bladder cancer treatment in v...

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Bibliographic Details
Main Authors: Ye Liang, Yonghua Wang, Liping Wang, Zhijuan Liang, Dan Li, Xiaoyu Xu, Yuanbin Chen, Xuecheng Yang, Hongbo Zhang, Haitao Niu
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2021-02-01
Series:Bioactive Materials
Subjects:
siRNA delivery
Chitosan
Hyaluronic acid dialdehyde
CD44 targeting
Bladder cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X20301948

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