High CCR5 density on central memory CD4+ T cells in acute HIV-1 infection is mostly associated with rapid disease progression.

High CCR5 density on central memory CD4+ T cells in acute HIV-1 infection is mostly associated with rapid disease progression.

CD4+ central memory T cells play a critical role in the pathogenesis of simian immunodeficiency virus disease, and the CCR5 density on the surface of CD4 T cells is an important factor in human immunodeficiency virus (HIV)-1 disease progression. We hypothesized that quantifying central memory cells...

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Bibliographic Details
Main Authors: Xue Yang, Yan-mei Jiao, Rui Wang, Yun-xia Ji, Hong-wei Zhang, Yong-hong Zhang, De-xi Chen, Tong Zhang, Hao Wu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3504013?pdf=render

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