Contributions of lipopolysaccharide and the type IVB secretion system to Coxiella burnetii vaccine efficacy and reactogenicity

Contributions of lipopolysaccharide and the type IVB secretion system to Coxiella burnetii vaccine efficacy and reactogenicity

Abstract Coxiella burnetii is the bacterial causative agent of the zoonosis Q fever. The current human Q fever vaccine, Q-VAX®, is a fixed, whole cell vaccine (WCV) licensed solely for use in Australia. C. burnetii WCV administration is associated with a dermal hypersensitivity reaction in people wi...

Full description

Bibliographic Details
Main Authors: Carrie M. Long, Paul A. Beare, Diane C. Cockrell, Jonathan Fintzi, Mahelat Tesfamariam, Carl I. Shaia, Robert A. Heinzen
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-021-00296-6

Similar Items

Similar Items