Aberrant Expression of <i>TLR2</i>,<i> TLR7</i>, <i>TLR9</i>, Splicing Variants of <i>TLR4</i> and <i>MYD88</i> in Chronic Lymphocytic Leukemia Patients

Aberrant Expression of <i>TLR2</i>,<i> TLR7</i>, <i>TLR9</i>, Splicing Variants of <i>TLR4</i> and <i>MYD88</i> in Chronic Lymphocytic Leukemia Patients

Functional toll-like receptors (TLRs) could modulate anti-tumor effects by activating inflammatory cytokines and the cytotoxic T-cells response. However, excessive TLR expression could promote tumor progression, since TLR-induced inflammation might stimulate cancer cells expansion into the microenvi...

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Bibliographic Details
Main Authors: Katarzyna Skorka, Paulina Wlasiuk, Agnieszka Karczmarczyk, Krzysztof Giannopoulos
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Journal of Clinical Medicine
Subjects:
CLL (chronic lymphocytic leukemia)
TLRs (toll-like receptors)
Myd88 (myeloid differentiation primary response protein 88)
Online Access:https://www.mdpi.com/2077-0383/10/4/867

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