Pro-Nerve Growth Factor Induces Activation of RhoA Kinase and Neuronal Cell Death

Pro-Nerve Growth Factor Induces Activation of RhoA Kinase and Neuronal Cell Death

We have previously shown that the expression of pro-nerve growth factor (proNGF) was significantly increased, nerve growth factor (NGF) level was decreased, and the expression of p75<sup>NTR</sup> was enhanced in Alzheimer&#8217;s disease (AD) hippocampal samples. NGF regulates cell...

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Bibliographic Details
Main Authors: Marina Sycheva, Jake Sustarich, Yuxian Zhang, Vaithinathan Selvaraju, Thangiah Geetha, Marla Gearing, Jeganathan Ramesh Babu
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Brain Sciences
Subjects:
NGF
proNGF
p75<sup>NTR</sup>
Alzheimer’s disease
RhoA kinase
neuronal death
Online Access:https://www.mdpi.com/2076-3425/9/8/204

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