Turnover of brain DHA in mice is accurately determined by tracer-free natural abundance carbon isotope ratio analysis

The brain is highly enriched in the long-chain omega-3 (n-3) PUFA DHA. Due to the limited capacity for local DHA synthesis in the brain, it relies on a continual supply from the circulation to replenish metabolized DHA. Previous studies investigating brain DHA turnover and metabolism have relied on...

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Bibliographic Details
Main Authors: R.J. Scott Lacombe, Chi-Chiu Lee, Richard P. Bazinet
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520300213