Hypothyroidism Intensifies Both Canonic and the <i>De Novo</i> Pathway of Peroxisomal Biogenesis in Rat Brown Adipocytes in a Time-Dependent Manner

Hypothyroidism Intensifies Both Canonic and the <i>De Novo</i> Pathway of Peroxisomal Biogenesis in Rat Brown Adipocytes in a Time-Dependent Manner

Despite peroxisomes being important partners of mitochondria by carrying out fatty acid oxidation in brown adipocytes, no clear evidence concerning peroxisome origin and way(s) of biogenesis exists. Herein we used methimazole-induced hypothyroidism for 7, 15, and 21 days to study peroxisomal remodel...

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Bibliographic Details
Main Authors: Marija Aleksic, Igor Golic, Andjelika Kalezic, Aleksandra Jankovic, Bato Korac, Aleksandra Korac
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cells
Subjects:
hypothyroidism
brown adipocyte
peroxisome
biogenesis pathway
inter-organellar association
Online Access:https://www.mdpi.com/2073-4409/10/9/2248

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