Multi-Spectral Clinical Prototype for Fluorophore Detection

Identification of tumour margins during resection of the brain is critical for improving the post-operative outcomes. Current methods of tumour identification use 5-ALA, an exogenous precursor, metabolized to fluorescent PpIX in tumour tissue. Although visible under fluorescent microscope, PpIX is e...

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Bibliographic Details
Main Authors: Konstantin Grygoryev , Huihui Lu , Celina L. Li , Alexander V. Zhdanov , Ray Burke , Stefan Andersson-Engels 
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Physics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphy.2021.724962/full