The landscape and driver potential of site-specific hotspots across cancer genomes

Abstract Large sets of whole cancer genomes make it possible to study mutation hotspots genome-wide. Here we detect, categorize, and characterize site-specific hotspots using 2279 whole cancer genomes from the Pan-Cancer Analysis of Whole Genomes project and provide a resource of annotated hotspots...

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Bibliographic Details
Main Authors: Randi Istrup Juul, Morten Muhlig Nielsen, Malene Juul, Lars Feuerbach, Jakob Skou Pedersen
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:npj Genomic Medicine
Online Access:https://doi.org/10.1038/s41525-021-00197-6

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