IRE1-independent gain control of the unfolded protein response.

Nonconventional splicing of the gene encoding the Hac1p transcription activator regulates the unfolded protein response (UPR) in Saccharomyces cerevisiae. This simple on/off switch contrasts with a more complex circuitry in higher eukaryotes. Here we show that a heretofore unrecognized pathway opera...

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Bibliographic Details
Main Authors: Jess H Leber, Sebastián Bernales, Peter Walter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2004-08-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC509300?pdf=render