Insulin Receptor Expression and Activity in the Brains of Nondiabetic Sporadic Alzheimer’s Disease Cases

Insulin Receptor Expression and Activity in the Brains of Nondiabetic Sporadic Alzheimer’s Disease Cases

We investigated the contents of the insulin receptor-beta subunit (IRβ) and [Tyr1162/1163]-phosphorylated IRβ as surrogate indices of total IR content and IR activation in postmortem hippocampal formation brain specimens from nondiabetic sporadic Alzheimer’s disease (AD) cases. We found no significa...

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Bibliographic Details
Main Authors:	Lap Ho, Shrishailam Yemul, Lindsay Knable, Pavel Katsel, Rudy Zhao, Vahram Haroutunian, Giulio Maria Pasinetti
Format:	Article
Language:	English
Published:	Hindawi Limited 2012-01-01
Series:	International Journal of Alzheimer's Disease
Online Access:	http://dx.doi.org/10.1155/2012/321280

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