Chemical Patterns of Proteasome Inhibitors: Lessons Learned from Two Decades of Drug Design

Chemical Patterns of Proteasome Inhibitors: Lessons Learned from Two Decades of Drug Design

Drug discovery now faces a new challenge, where the availability of experimental data is no longer the limiting step, and instead, making sense of the data has gained a new level of importance, propelled by the extensive incorporation of cheminformatics and bioinformatics methodologies into the drug...

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Bibliographic Details
Main Authors: Romina A. Guedes, Natália Aniceto, Marina A. P. Andrade, Jorge A. R. Salvador, Rita C. Guedes
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:International Journal of Molecular Sciences
Subjects:
proteasome
proteasome inhibitors
molecular descriptors
fingerprints
chemical space
decision tree
structure-activity relationship
Online Access:https://www.mdpi.com/1422-0067/20/21/5326

Internet

https://www.mdpi.com/1422-0067/20/21/5326

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