Pathways for Oral and Rectal Delivery of Gold Nanoparticles (1.7 nm) and Gold Nanoclusters into the Colon: Enteric-Coated Capsules and Suppositories

Pathways for Oral and Rectal Delivery of Gold Nanoparticles (1.7 nm) and Gold Nanoclusters into the Colon: Enteric-Coated Capsules and Suppositories

Two ways to deliver ultrasmall gold nanoparticles and gold-bovine serum albumin (BSA) nanoclusters to the colon were developed. First, oral administration is possible by incorporation into gelatin capsules that were coated with an enteric polymer. These permit the transfer across the stomach whose a...

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Bibliographic Details
Main Authors: Shabnam Hosseini, Oliver Wetzel, Kathrin Kostka, Marc Heggen, Kateryna Loza, Matthias Epple
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Molecules
Subjects:
capsules
colon
drug delivery
gold
nanoparticles
suppositories
Online Access:https://www.mdpi.com/1420-3049/26/16/5069

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