Simultaneous correlative scanning electron and high-NA fluorescence microscopy.

Correlative light and electron microscopy (CLEM) is a unique method for investigating biological structure-function relations. With CLEM protein distributions visualized in fluorescence can be mapped onto the cellular ultrastructure measured with electron microscopy. Widespread application of correl...

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Bibliographic Details
Main Authors: Nalan Liv, A Christiaan Zonnevylle, Angela C Narvaez, Andries P J Effting, Philip W Voorneveld, Miriam S Lucas, James C Hardwick, Roger A Wepf, Pieter Kruit, Jacob P Hoogenboom
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3568124?pdf=render