Time-course microarrays reveal early activation of the immune transcriptome and adipokine dysregulation leads to fibrosis in visceral adipose depots during diet-induced obesity

Time-course microarrays reveal early activation of the immune transcriptome and adipokine dysregulation leads to fibrosis in visceral adipose depots during diet-induced obesity

<p>Abstract</p> <p>Background</p> <p>Visceral white adipose tissue (WAT) hypertrophy, adipokine production, inflammation and fibrosis are strongly associated with obesity, but the time-course of these changes <it>in-vivo</it> are not fully understood. Theref...

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Bibliographic Details
Main Authors: Kwon Eun-Young, Shin Su-Kyung, Cho Yun-Young, Jung Un, Kim Eunjung, Park Taesun, Park Jung Han, Yun Jong, McGregor Robin A, Park Yong, Choi Myung-Sook
Format: Article
Language:English
Published: BMC 2012-09-01
Series:BMC Genomics
Subjects:
Adipocytokine dysregulation
Transcriptional response
Adipose tissue
Extracellular matrix
Cathepsin
Fibrosis
Online Access:http://www.biomedcentral.com/1471-2164/13/450

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