A Novel, Rapid, and Low-Volume Assay for Therapeutic Drug Monitoring of Posaconazole and Other Long-Chain Azole-Class Antifungal Drugs

A Novel, Rapid, and Low-Volume Assay for Therapeutic Drug Monitoring of Posaconazole and Other Long-Chain Azole-Class Antifungal Drugs

This work describes an effective assay for TDM of long-chain azole-class antifungal drugs that can be used in diluted human serum samples. This assay will provide a quick, cost-effective method for monitoring concentrations of drugs such as posaconazole that exhibit well-documented pharmacokinetic v...

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Bibliographic Details
Main Authors:	Gregory R. Wiedman, Yanan Zhao, David S. Perlin
Format:	Article
Language:	English
Published:	American Society for Microbiology 2018-12-01
Series:	mSphere
Subjects:	azole-class antifungal drugs bioassay biochemistry biotechnology graphene nanotechnology synthetic biology therapeutic drug monitoring
Online Access:	https://doi.org/10.1128/mSphere.00623-18

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