Effect of Lipopolysaccharide and TNFα on Neuronal Ascorbic Acid Uptake

Effect of Lipopolysaccharide and TNFα on Neuronal Ascorbic Acid Uptake

Vitamin C (ascorbic acid: AA) uptake in neurons occurs via the sodium-dependent vitamin C transporter-2 (SVCT2), which is highly expressed in the central nervous system (CNS). During chronic neuroinflammation or infection, CNS levels of lipopolysaccharide (LPS) and LPS-induced tumor necrosis factor-...

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Bibliographic Details
Main Authors:	Veedamali S. Subramanian, Trevor Teafatiller, Anshu Agrawal, Masashi Kitazawa, Jonathan S. Marchant
Format:	Article
Language:	English
Published:	Hindawi Limited 2021-01-01
Series:	Mediators of Inflammation
Online Access:	http://dx.doi.org/10.1155/2021/4157132

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