Assessing Advantages and Drawbacks of Rapidly Generated Ultra-Large 3D Breast Cancer Spheroids: Studies with Chemotherapeutics and Nanoparticles

Assessing Advantages and Drawbacks of Rapidly Generated Ultra-Large 3D Breast Cancer Spheroids: Studies with Chemotherapeutics and Nanoparticles

Traditionally, two-dimensional (2D) monolayer cell culture models have been used to study in vitro conditions for their ease of use, simplicity and low cost. However, recently, three-dimensional (3D) cell culture models have been heavily investigated as they provide better physiological relevance fo...

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Bibliographic Details
Main Authors: Austin R. Holub, Anderson Huo, Kavil Patel, Vishal Thakore, Pranav Chhibber, Folarin Erogbogbo
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:International Journal of Molecular Sciences
Subjects:
spheroids
nanoparticles
doxorubicin
ultra-large spheroids
chemotherapeutics
doxil
Online Access:https://www.mdpi.com/1422-0067/21/12/4413

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