Silencing of ELK3 Induces S-M Phase Arrest and Apoptosis and Upregulates SERPINE1 Expression Reducing Migration in Prostate Cancer Cells

Silencing of ELK3 Induces S-M Phase Arrest and Apoptosis and Upregulates SERPINE1 Expression Reducing Migration in Prostate Cancer Cells

ELK3, an ETS domain-containing transcription factor, participates in various physiological and pathological processes including cell proliferation, migration, angiogenesis, and malignant progression. However, the role of ELK3 in prostate cancer cells and its mechanism are not fully understood. The c...

Full description

Bibliographic Details
Main Authors:	Yuanshen Mao, Wenfeng Li, Bao Hua, Xin Gu, Weixin Pan, Qi Chen, Bin Xu, Zhong Wang, Chao Lu
Format:	Article
Language:	English
Published:	Hindawi Limited 2020-01-01
Series:	BioMed Research International
Online Access:	http://dx.doi.org/10.1155/2020/2406159

Similar Items

Circular RNA_PDHX Promotes the Proliferation and Invasion of Prostate Cancer by Sponging MiR-378a-3p
by: Yuanshen Mao, et al.
Published: (2021-01-01)

Serpin functions in host-pathogen interactions
by: Jialing Bao, et al.
Published: (2018-04-01)

Silencing of mutant p53 by siRNA induces cell cycle arrest and apoptosis in human bladder cancer cells
by: Zhu Hai-Bin, et al.
Published: (2013-01-01)

Silencing of PSMC2 inhibits development and metastasis of prostate cancer through regulating proliferation, apoptosis and migration
by: Qingke Chen, et al.
Published: (2021-04-01)

Oncostatin M mediates STAT3-dependent intestinal epithelial restitution via increased cell proliferation, decreased apoptosis and upregulation of SERPIN family members.
by: Florian Beigel, et al.
Published: (2014-01-01)

The bioengineering of targeted serpins
by: Crowther, Damian C.
Published: (1992)

The heparin activateable serpins
by: Evans, Dyfed Ll
Published: (1991)

The serpin hinge region
by: Hopkins, Paul Charles Richard
Published: (1993)

PPAR-γ Silencing Inhibits the Apoptosis of A549 Cells by Upregulating Bcl-2
by: Jingyu YANG
Published: (2013-03-01)

SLC1A5 Silencing Inhibits Esophageal Cancer Growth via Cell Cycle Arrest and Apoptosis
by: Jieping Lin, et al.
Published: (2018-08-01)

The Isochaihulactone-induced cell cycle arrest and apoptosis in human prostate cancer
by: HUNG CHIH CHANG, et al.
Published: (2010)

SERPINs—From Trap to Treatment
by: Wariya Sanrattana, et al.
Published: (2019-02-01)

The serpins : structure: function relationships
by: Pemberton, Philip A.
Published: (1989)

Conformational mobility and interactions of the serpins
by: Chang, Wun-Shaing Wayne
Published: (1995)

The nature of serpine-enzyme complexes
by: Hermans, Josephine Margaret
Published: (1993)

Serpin expression and structural studies
by: Baek, Kyuwon
Published: (2004)

Small Molecules Binding to Serpins
by: Afridi, Junaid
Published: (2006)

Therapeutic SERPINs: Improving on Nature
by: Coen Maas, et al.
Published: (2021-03-01)

ELK1-induced upregulation of long non-coding RNA MIR100HG predicts poor prognosis and promotes the progression of osteosarcoma by epigenetically silencing LATS1 and LATS2
by: Xiaochuan Su, et al.
Published: (2019-01-01)

Hepatits C virus down-regulates the expression of SERPIN D1 and SERPIN E1
by: Tzu-Shan Ku, et al.
Published: (2016)

SerpinA3N is a novel hypothalamic gene upregulated by a high-fat diet and leptin in mice
by: Domenico Sergi, et al.
Published: (2018-11-01)

The Elk's Arrival
by: Beardsley, John
Published: (2010)

The elk in Virginia
by: Wood, Roy K.
Published: (2015)

Inhibition of melanization by serpin-5 and serpin-9 promotes baculovirus infection in cotton bollworm Helicoverpa armigera.
by: Chuanfei Yuan, et al.
Published: (2017-09-01)

Silencing of long noncoding RNA PVT1 inhibits podocyte damage and apoptosis in diabetic nephropathy by upregulating FOXA1
by: Dong-Wei Liu, et al.
Published: (2019-08-01)

MALAT1 silencing suppresses prostate cancer progression by upregulating miR-1 and downregulating KRAS
by: Chang J, et al.
Published: (2018-06-01)

PPARγ-independent induction of growth arrest and apoptosis in prostate and bladder carcinoma
by: Thomas David M, et al.
Published: (2006-03-01)

Spatiotemporal expression of SERPINE2 in the human placenta and its role in extravillous trophoblast migration and invasion
by: Chang Hsiao-Ho, et al.
Published: (2011-08-01)

Aberrant elevation of GDF8 impairs granulosa cell glucose metabolism via upregulating SERPINE1 expression in patients with PCOS
by: Long Bai, et al.
Published: (2021-03-01)

Inhibition of HCV by the serpin antithrombin III
by: Asmal Mohammed, et al.
Published: (2012-10-01)

Structure and function of non-inhibitory serpins
by: Stein, Penelope E.
Published: (1990)

Scaling Concepts in Serpin Polymer Physics
by: Samuele Raccosta, et al.
Published: (2021-05-01)

Information for the Elk Herd Debate in Arizona: Tracking Elk Populations by Satellite
by: Littlefield, Joanne
Published: (2001)

IgM-linked SerpinB3 and SerpinB4 in sera of patients with chronic liver disease.
by: Alessandra Biasiolo, et al.
Published: (2012-01-01)

Preferential binding to Elk-1 by SLE-associated IL10 risk allele upregulates IL10 expression.
by: Daisuke Sakurai, et al.
Published: (2013-01-01)

Regulation of DNA synthesis and the cell cycle in human prostate cancer cells and lymphocytes by ovine uterine serpin
by: Hansen Peter J, et al.
Published: (2008-01-01)

βKlotho Inhibits Cell Proliferation by Downregulating ELK4 and Predicts Favorable Prognosis in Prostate Cancer
by: Mao C, et al.
Published: (2021-08-01)

Interactions between moose, elk and buffalo in Elk Island National Park, Alberta
by: Holsworth, William Norton
Published: (2012)

ESTABLISHMENT OF SEROLOGICAL REFERENCE RANGES FOR ELK IN KENTUCKY AND EFFECTS OF QUARANTINE AND TRANSLOCATION ON ELK
by: Hildreth, Aaron M.
Published: (2017)

Upregulation of RND3 Affects Trophoblast Proliferation, Apoptosis, and Migration at the Maternal-Fetal Interface
by: Xiao-Ling Ma, et al.
Published: (2020-03-01)