GLD-4-mediated translational activation regulates the size of the proliferative germ cell pool in the adult C. elegans germ line.
To avoid organ dysfunction as a consequence of tissue diminution or tumorous growth, a tight balance between cell proliferation and differentiation is maintained in metazoans. However, cell-intrinsic gene expression mechanisms controlling adult tissue homeostasis remain poorly understood. By focusin...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-09-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC4177745?pdf=render |