Enterovirus 71 infection causes severe pulmonary lesions in gerbils, meriones unguiculatus, which can be prevented by passive immunization with specific antisera.

Enterovirus 71 infection causes severe pulmonary lesions in gerbils, meriones unguiculatus, which can be prevented by passive immunization with specific antisera.

Neurogenic pulmonary edema caused by severe brainstem encephalitis is the leading cause of death in young children infected by Enterovirus 71 (EV71). However, no pulmonary lesions have been found in EV71-infected transgenic or non-transgenic mouse models. Development of a suitable animal model is im...

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Bibliographic Details
Main Authors: Fang Xu, Ping-Ping Yao, Yong Xia, Lei Qian, Zhang-Nv Yang, Rong-Hui Xie, Yi-Sheng Sun, Hang-Jing Lu, Zi-Ping Miao, Chan Li, Xiao Li, Wei-Feng Liang, Xiao-Xiao Huang, Shi-Chang Xia, Zhi-Ping Chen, Jian-Min Jiang, Yan-Jun Zhang, Ling-Ling Mei, She-Lan Liu, Hua Gu, Zhi-Yao Xu, Xiao-Fei Fu, Zhi-Yong Zhu, Han-Ping Zhu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0119173

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