DNA methylation status of nuclear-encoded mitochondrial genes underlies the tissue-dependent mitochondrial functions

<p>Abstract</p> <p>Background</p> <p>Mitochondria are semi-autonomous, semi-self-replicating organelles harboring their own DNA (mitochondrial DNA, mtDNA), and their dysregulation is involved in the development of various diseases. While mtDNA does not generally undergo...

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Bibliographic Details
Main Authors: Takasugi Masaki, Yagi Shintaro, Hirabayashi Keiji, Shiota Kunio
Format: Article
Language:English
Published: BMC 2010-08-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/11/481