T Regulatory Cells and Priming the Suppressive Tumor Microenvironment

T Regulatory Cells and Priming the Suppressive Tumor Microenvironment

Treg play a central role in maintenance of self tolerance and homeostasis through suppression of self-reactive T cell populations. In addition to that role, Treg also survey cancers and suppress anti-tumor immune responses. Thus, understanding the unique attributes of Treg-tumor interactions may per...

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Bibliographic Details
Main Authors: Christina M. Paluskievicz, Xuefang Cao, Reza Abdi, Pan Zheng, Yang Liu, Jonathan S. Bromberg
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Immunology
Subjects:
Treg
immunosuppression
tumor microenvironment
metastasis
anti-tumor immunity
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02453/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02453/full

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