One day wonder: Fast resolution of macular edema following intravitreal ranibizumab in retinal venous occlusions
Macular edema is a significant cause of vision loss in patients with central retinal vein occlusions and branch retinal vein occlusions. Vascular endothelial growth factor (VEGF) appears to be a key factor in the pathogenesis of this disease. Anti-VEGF therapy, such as intravitreal ranibizumab provi...
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doaj-cf868ac49e5e4a7894b0c69f1ef5ba092020-11-24T23:52:48ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892013-01-0161952853010.4103/0301-4738.119458One day wonder: Fast resolution of macular edema following intravitreal ranibizumab in retinal venous occlusionsLalit VermaArindam ChakravartiAvnindra GuptaSmriti PrakashMacular edema is a significant cause of vision loss in patients with central retinal vein occlusions and branch retinal vein occlusions. Vascular endothelial growth factor (VEGF) appears to be a key factor in the pathogenesis of this disease. Anti-VEGF therapy, such as intravitreal ranibizumab provides an effective treatment against vision-threatening macular edema. We report three patients of retinal vein occlusion with macular edema who demonstrated overnight resolution of macular edema following treatment with intravitreal ranibizumab (0.5 mg). 3D optical coherence tomography (Optovue) was used as a tool for comparison of the macular thickness before and after treatment. The significant reductions in the central foveal thickness demonstrated in these patients one night after intravitreal injections could have significant influence on modifying current treatment protocols. Early treatment of macular edema related to retinal venous occlusive disease with anti-VEGF injections could result in faster visual rehabilitation in these patients.http://www.ijo.in/article.asp?issn=0301-4738;year=2013;volume=61;issue=9;spage=528;epage=530;aulast=VermaChemotherapyfocal treatmentretinoblastomaAllergic eye diseasepapillaeshield ulcervernal keratoconjunctivitisAnti-VEGF injectionsbevacizumabneovascular age-related macular degenerationranibizumabsubmacular hemorrhageEmergency departmentoculartraumawork related injuriesOcular traumaopen globe injurypreoperative (initial) visual acuityprognostic factorsrelative afferent pupillary defectConfigurationchoroidal neovascular membranefoveal slopefoveal thicknessneovascular age-related macular degenerationmacular pigmentDescemet membranekeratoplastyoptical coherence tomographyCentral serous chorioretinopathyepidural steroidretinal pigment epithelium detachmentretinal pigment epithelium tearSelf-inflictedocular injuryneedleAnterior chamber maintainerbest corrected visual acuityneodymium yttrium aluminium garnet laserocular visco-surgical deviceposterior capsule opacificationAIDSCandida albicansreverse masquerade syndromeBevacizumabcomplicationsintravitreal injectionScytalidium sp.CefepimeceftazidimeendophthalmitisPseudomonas aeruginosaMacular edemaoptical coherence tomographyranibizumabretinal vein occlusionvascular endothelial growth factor |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Lalit Verma Arindam Chakravarti Avnindra Gupta Smriti Prakash |
spellingShingle |
Lalit Verma Arindam Chakravarti Avnindra Gupta Smriti Prakash One day wonder: Fast resolution of macular edema following intravitreal ranibizumab in retinal venous occlusions Indian Journal of Ophthalmology Chemotherapy focal treatment retinoblastoma Allergic eye disease papillae shield ulcer vernal keratoconjunctivitis Anti-VEGF injections bevacizumab neovascular age-related macular degeneration ranibizumab submacular hemorrhage Emergency department ocular trauma work related injuries Ocular trauma open globe injury preoperative (initial) visual acuity prognostic factors relative afferent pupillary defect Configuration choroidal neovascular membrane foveal slope foveal thickness neovascular age-related macular degeneration macular pigment Descemet membrane keratoplasty optical coherence tomography Central serous chorioretinopathy epidural steroid retinal pigment epithelium detachment retinal pigment epithelium tear Self-inflicted ocular injury needle Anterior chamber maintainer best corrected visual acuity neodymium yttrium aluminium garnet laser ocular visco-surgical device posterior capsule opacification AIDS Candida albicans reverse masquerade syndrome Bevacizumab complications intravitreal injection Scytalidium sp. Cefepime ceftazidime endophthalmitis Pseudomonas aeruginosa Macular edema optical coherence tomography ranibizumab retinal vein occlusion vascular endothelial growth factor |
author_facet |
Lalit Verma Arindam Chakravarti Avnindra Gupta Smriti Prakash |
author_sort |
Lalit Verma |
title |
One day wonder: Fast resolution of macular edema following intravitreal ranibizumab in retinal venous occlusions |
title_short |
One day wonder: Fast resolution of macular edema following intravitreal ranibizumab in retinal venous occlusions |
title_full |
One day wonder: Fast resolution of macular edema following intravitreal ranibizumab in retinal venous occlusions |
title_fullStr |
One day wonder: Fast resolution of macular edema following intravitreal ranibizumab in retinal venous occlusions |
title_full_unstemmed |
One day wonder: Fast resolution of macular edema following intravitreal ranibizumab in retinal venous occlusions |
title_sort |
one day wonder: fast resolution of macular edema following intravitreal ranibizumab in retinal venous occlusions |
publisher |
Wolters Kluwer Medknow Publications |
series |
Indian Journal of Ophthalmology |
issn |
0301-4738 1998-3689 |
publishDate |
2013-01-01 |
description |
Macular edema is a significant cause of vision loss in patients with central retinal vein occlusions and branch retinal vein occlusions. Vascular endothelial growth factor (VEGF) appears to be a key factor in the pathogenesis of this disease. Anti-VEGF therapy, such as intravitreal ranibizumab provides an effective treatment against vision-threatening macular edema. We report three patients of retinal vein occlusion with macular edema who demonstrated overnight resolution of macular edema following treatment with intravitreal ranibizumab (0.5 mg). 3D optical coherence tomography (Optovue) was used as a tool for comparison of the macular thickness before and after treatment. The significant reductions in the central foveal thickness demonstrated in these patients one night after intravitreal injections could have significant influence on modifying current treatment protocols. Early treatment of macular edema related to retinal venous occlusive disease with anti-VEGF injections could result in faster visual rehabilitation in these patients. |
topic |
Chemotherapy focal treatment retinoblastoma Allergic eye disease papillae shield ulcer vernal keratoconjunctivitis Anti-VEGF injections bevacizumab neovascular age-related macular degeneration ranibizumab submacular hemorrhage Emergency department ocular trauma work related injuries Ocular trauma open globe injury preoperative (initial) visual acuity prognostic factors relative afferent pupillary defect Configuration choroidal neovascular membrane foveal slope foveal thickness neovascular age-related macular degeneration macular pigment Descemet membrane keratoplasty optical coherence tomography Central serous chorioretinopathy epidural steroid retinal pigment epithelium detachment retinal pigment epithelium tear Self-inflicted ocular injury needle Anterior chamber maintainer best corrected visual acuity neodymium yttrium aluminium garnet laser ocular visco-surgical device posterior capsule opacification AIDS Candida albicans reverse masquerade syndrome Bevacizumab complications intravitreal injection Scytalidium sp. Cefepime ceftazidime endophthalmitis Pseudomonas aeruginosa Macular edema optical coherence tomography ranibizumab retinal vein occlusion vascular endothelial growth factor |
url |
http://www.ijo.in/article.asp?issn=0301-4738;year=2013;volume=61;issue=9;spage=528;epage=530;aulast=Verma |
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