One day wonder: Fast resolution of macular edema following intravitreal ranibizumab in retinal venous occlusions

Macular edema is a significant cause of vision loss in patients with central retinal vein occlusions and branch retinal vein occlusions. Vascular endothelial growth factor (VEGF) appears to be a key factor in the pathogenesis of this disease. Anti-VEGF therapy, such as intravitreal ranibizumab provi...

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Main Authors: Lalit Verma, Arindam Chakravarti, Avnindra Gupta, Smriti Prakash
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2013-01-01
Series:Indian Journal of Ophthalmology
Subjects:
Online Access:http://www.ijo.in/article.asp?issn=0301-4738;year=2013;volume=61;issue=9;spage=528;epage=530;aulast=Verma
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spelling doaj-cf868ac49e5e4a7894b0c69f1ef5ba092020-11-24T23:52:48ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892013-01-0161952853010.4103/0301-4738.119458One day wonder: Fast resolution of macular edema following intravitreal ranibizumab in retinal venous occlusionsLalit VermaArindam ChakravartiAvnindra GuptaSmriti PrakashMacular edema is a significant cause of vision loss in patients with central retinal vein occlusions and branch retinal vein occlusions. Vascular endothelial growth factor (VEGF) appears to be a key factor in the pathogenesis of this disease. Anti-VEGF therapy, such as intravitreal ranibizumab provides an effective treatment against vision-threatening macular edema. We report three patients of retinal vein occlusion with macular edema who demonstrated overnight resolution of macular edema following treatment with intravitreal ranibizumab (0.5 mg). 3D optical coherence tomography (Optovue) was used as a tool for comparison of the macular thickness before and after treatment. The significant reductions in the central foveal thickness demonstrated in these patients one night after intravitreal injections could have significant influence on modifying current treatment protocols. Early treatment of macular edema related to retinal venous occlusive disease with anti-VEGF injections could result in faster visual rehabilitation in these patients.http://www.ijo.in/article.asp?issn=0301-4738;year=2013;volume=61;issue=9;spage=528;epage=530;aulast=VermaChemotherapyfocal treatmentretinoblastomaAllergic eye diseasepapillaeshield ulcervernal keratoconjunctivitisAnti-VEGF injectionsbevacizumabneovascular age-related macular degenerationranibizumabsubmacular hemorrhageEmergency departmentoculartraumawork related injuriesOcular traumaopen globe injurypreoperative (initial) visual acuityprognostic factorsrelative afferent pupillary defectConfigurationchoroidal neovascular membranefoveal slopefoveal thicknessneovascular age-related macular degenerationmacular pigmentDescemet membranekeratoplastyoptical coherence tomographyCentral serous chorioretinopathyepidural steroidretinal pigment epithelium detachmentretinal pigment epithelium tearSelf-inflictedocular injuryneedleAnterior chamber maintainerbest corrected visual acuityneodymium yttrium aluminium garnet laserocular visco-surgical deviceposterior capsule opacificationAIDSCandida albicansreverse masquerade syndromeBevacizumabcomplicationsintravitreal injectionScytalidium sp.CefepimeceftazidimeendophthalmitisPseudomonas aeruginosaMacular edemaoptical coherence tomographyranibizumabretinal vein occlusionvascular endothelial growth factor
collection DOAJ
language English
format Article
sources DOAJ
author Lalit Verma
Arindam Chakravarti
Avnindra Gupta
Smriti Prakash
spellingShingle Lalit Verma
Arindam Chakravarti
Avnindra Gupta
Smriti Prakash
One day wonder: Fast resolution of macular edema following intravitreal ranibizumab in retinal venous occlusions
Indian Journal of Ophthalmology
Chemotherapy
focal treatment
retinoblastoma
Allergic eye disease
papillae
shield ulcer
vernal keratoconjunctivitis
Anti-VEGF injections
bevacizumab
neovascular age-related macular degeneration
ranibizumab
submacular hemorrhage
Emergency department
ocular
trauma
work related injuries
Ocular trauma
open globe injury
preoperative (initial) visual acuity
prognostic factors
relative afferent pupillary defect
Configuration
choroidal neovascular membrane
foveal slope
foveal thickness
neovascular age-related macular degeneration
macular pigment
Descemet membrane
keratoplasty
optical coherence tomography
Central serous chorioretinopathy
epidural steroid
retinal pigment epithelium detachment
retinal pigment epithelium tear
Self-inflicted
ocular injury
needle
Anterior chamber maintainer
best corrected visual acuity
neodymium yttrium aluminium garnet laser
ocular visco-surgical device
posterior capsule opacification
AIDS
Candida albicans
reverse masquerade syndrome
Bevacizumab
complications
intravitreal injection
Scytalidium sp.
Cefepime
ceftazidime
endophthalmitis
Pseudomonas aeruginosa
Macular edema
optical coherence tomography
ranibizumab
retinal vein occlusion
vascular endothelial growth factor
author_facet Lalit Verma
Arindam Chakravarti
Avnindra Gupta
Smriti Prakash
author_sort Lalit Verma
title One day wonder: Fast resolution of macular edema following intravitreal ranibizumab in retinal venous occlusions
title_short One day wonder: Fast resolution of macular edema following intravitreal ranibizumab in retinal venous occlusions
title_full One day wonder: Fast resolution of macular edema following intravitreal ranibizumab in retinal venous occlusions
title_fullStr One day wonder: Fast resolution of macular edema following intravitreal ranibizumab in retinal venous occlusions
title_full_unstemmed One day wonder: Fast resolution of macular edema following intravitreal ranibizumab in retinal venous occlusions
title_sort one day wonder: fast resolution of macular edema following intravitreal ranibizumab in retinal venous occlusions
publisher Wolters Kluwer Medknow Publications
series Indian Journal of Ophthalmology
issn 0301-4738
1998-3689
publishDate 2013-01-01
description Macular edema is a significant cause of vision loss in patients with central retinal vein occlusions and branch retinal vein occlusions. Vascular endothelial growth factor (VEGF) appears to be a key factor in the pathogenesis of this disease. Anti-VEGF therapy, such as intravitreal ranibizumab provides an effective treatment against vision-threatening macular edema. We report three patients of retinal vein occlusion with macular edema who demonstrated overnight resolution of macular edema following treatment with intravitreal ranibizumab (0.5 mg). 3D optical coherence tomography (Optovue) was used as a tool for comparison of the macular thickness before and after treatment. The significant reductions in the central foveal thickness demonstrated in these patients one night after intravitreal injections could have significant influence on modifying current treatment protocols. Early treatment of macular edema related to retinal venous occlusive disease with anti-VEGF injections could result in faster visual rehabilitation in these patients.
topic Chemotherapy
focal treatment
retinoblastoma
Allergic eye disease
papillae
shield ulcer
vernal keratoconjunctivitis
Anti-VEGF injections
bevacizumab
neovascular age-related macular degeneration
ranibizumab
submacular hemorrhage
Emergency department
ocular
trauma
work related injuries
Ocular trauma
open globe injury
preoperative (initial) visual acuity
prognostic factors
relative afferent pupillary defect
Configuration
choroidal neovascular membrane
foveal slope
foveal thickness
neovascular age-related macular degeneration
macular pigment
Descemet membrane
keratoplasty
optical coherence tomography
Central serous chorioretinopathy
epidural steroid
retinal pigment epithelium detachment
retinal pigment epithelium tear
Self-inflicted
ocular injury
needle
Anterior chamber maintainer
best corrected visual acuity
neodymium yttrium aluminium garnet laser
ocular visco-surgical device
posterior capsule opacification
AIDS
Candida albicans
reverse masquerade syndrome
Bevacizumab
complications
intravitreal injection
Scytalidium sp.
Cefepime
ceftazidime
endophthalmitis
Pseudomonas aeruginosa
Macular edema
optical coherence tomography
ranibizumab
retinal vein occlusion
vascular endothelial growth factor
url http://www.ijo.in/article.asp?issn=0301-4738;year=2013;volume=61;issue=9;spage=528;epage=530;aulast=Verma
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