Diabetic Muscle Infarction: A Rare End-Organ Vascular Complication of Diabetes

Diabetic muscle infarction (DMI) is a rare microvascular complication of spontaneous ischemic necrosis of skeletal muscle in patients with poorly controlled diabetes. We herein describe the case of a 26-year-old woman with a history of type I diabetes and accompanying diabetic microvascular complica...

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Bibliographic Details
Main Authors: Callie Seaman, Michael Amos, Adam M. Franks, Asher Sexton, Kimberly McClelland, Erika M. Harris
Format: Article
Language:English
Published: Marshall University 2019-10-01
Series:Marshall Journal of Medicine
Subjects:
Online Access:https://mds.marshall.edu/cgi/viewcontent.cgi?article=1232&context=mjm
Description
Summary:Diabetic muscle infarction (DMI) is a rare microvascular complication of spontaneous ischemic necrosis of skeletal muscle in patients with poorly controlled diabetes. We herein describe the case of a 26-year-old woman with a history of type I diabetes and accompanying diabetic microvascular complications of neuropathy, nephropathy and retinopathy, who presented with sudden onset of swelling and sharp pain in her bilateral thighs. T2-weighted MRI imaging revealed subcutaneous edema and sub-fascial, hyper-intense enhancement of proximal thigh musculature. DMI has a relatively non-specific clinical presentation; therefore, physician awareness is key for early diagnosis, as aggressive management has been associated with poor patient outcomes. With poor long-term prognosis and high reoccurrence, DMI acts as an indicator of vascular end-organ damage.
ISSN:2379-9536