Genome-wide association study of celiac disease in North America confirms FRMD4B as new celiac locus.

Genome-wide association study of celiac disease in North America confirms FRMD4B as new celiac locus.

We performed a genome-wide association study (GWAS) of 1550 North American celiac disease cases and 3084 controls. Twelve SNPs, distributed across four regions (3p21.31, 4q27, 6q15, 6q25), were significantly associated with disease (p-value <1.0×10-7), and a further seven SNPs, across four additi...

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Bibliographic Details
Main Authors: Chad Garner, Richard Ahn, Yuan Chun Ding, Linda Steele, Samantha Stoven, Peter H Green, Alessio Fasano, Joseph A Murray, Susan L Neuhausen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4084811?pdf=render

Internet

http://europepmc.org/articles/PMC4084811?pdf=render

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