Microglial activation in the right amygdala-entorhinal-hippocampal complex is associated with preserved spatial learning in AppNL-G-F mice

Microglial activation in the right amygdala-entorhinal-hippocampal complex is associated with preserved spatial learning in AppNL-G-F mice

Background: In Alzheimer`s disease (AD), regional heterogeneity of β-amyloid burden and microglial activation of individual patients is a well-known phenomenon. Recently, we described a high incidence of inter-individual regional heterogeneity in terms of asymmetry of plaque burden and microglial ac...

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Bibliographic Details
Main Authors: Gloria Biechele, Karin Wind, Tanja Blume, Christian Sacher, Leonie Beyer, Florian Eckenweber, Nicolai Franzmeier, Michael Ewers, Benedikt Zott, Simon Lindner, Franz-Josef Gildehaus, Barbara von Ungern-Sternberg, Sabina Tahirovic, Michael Willem, Peter Bartenstein, Paul Cumming, Axel Rominger, Jochen Herms, Matthias Brendel
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:NeuroImage
Subjects:
β-amyloid
microglia
regional heterogeneity
asymmetry
spatial learning
AppNL-G-F
Online Access:http://www.sciencedirect.com/science/article/pii/S1053811920311927

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http://www.sciencedirect.com/science/article/pii/S1053811920311927

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