Ectodermal influx and cell hypertrophy provide early growth for all murine mammary rudiments, and are differentially regulated among them by Gli3.

Ectodermal influx and cell hypertrophy provide early growth for all murine mammary rudiments, and are differentially regulated among them by Gli3.

Mammary gland development starts in utero with one or several pairs of mammary rudiments (MRs) budding from the surface ectodermal component of the mammalian embryonic skin. Mice develop five pairs, numbered MR1 to MR5 from pectoral to inguinal position. We have previously shown that Gli3(Xt-J/Xt-J)...

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Main Authors: May Yin Lee, Victor Racine, Peter Jagadpramana, Li Sun, Weimiao Yu, Tiehua Du, Bradley Spencer-Dene, Nicole Rubin, Lendy Le, Delphine Ndiaye, Saverio Bellusci, Klaus Kratochwil, Jacqueline M Veltmaat
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3203106?pdf=render

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