Identification of a novel de novo mutation associated with PRKAG2 cardiac syndrome and early onset of heart failure.

Identification of a novel de novo mutation associated with PRKAG2 cardiac syndrome and early onset of heart failure.

The major structure elements of the AMP-activated protein kinase (AMPK) are α, β, and γ sunbunits. Mutations in γ2 subunit (PRKAG2) have been associated with a cardiac syndrome including inherited ventricular preexcitation, conduction disorder and hypertrophy mimicking hypertrophic cardiomyopathy. T...

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Bibliographic Details
Main Authors: Yang Liu, Rong Bai, Lin Wang, Cuntai Zhang, Ruifu Zhao, Deli Wan, Xinshan Chen, Gabriel Caceres, Daniel Barr, Hector Barajas-Martinez, Charles Antzelevitch, Dan Hu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3669303?pdf=render

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http://europepmc.org/articles/PMC3669303?pdf=render

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