Crystal Structure of the Chloroplastic Glutamine Phosphoribosylpyrophosphate Amidotransferase GPRAT2 From Arabidopsis thaliana

Crystal Structure of the Chloroplastic Glutamine Phosphoribosylpyrophosphate Amidotransferase GPRAT2 From Arabidopsis thaliana

Chloroplastic glutamine phosphoribosylpyrophosphate amidotransferase (GPRATase) catalyzes the first committed step of de novo purine biosynthesis in Arabidopsis thaliana, and DAS734 is a direct and specific inhibitor of AtGPRAT, with phytotoxic effects similar to the leaf beaching phenotypes of know...

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Bibliographic Details
Main Authors: Xueli Cao, Bowen Du, Fengjiao Han, Yu Zhou, Junhui Ren, Wenhe Wang, Zeliang Chen, Yi Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Plant Science
Subjects:
chloroplastic glutamine phosphoribosylpyrophosphate amidotransferase
herbicide
X-ray crystallography
competitive inhibition
Arabidopsis thaliana
DAS734
Online Access:https://www.frontiersin.org/article/10.3389/fpls.2020.00157/full

Internet

https://www.frontiersin.org/article/10.3389/fpls.2020.00157/full

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