Dynamic Arc SUMOylation and Selective Interaction with F-Actin-Binding Protein Drebrin A in LTP Consolidation In Vivo

Dynamic Arc SUMOylation and Selective Interaction with F-Actin-Binding Protein Drebrin A in LTP Consolidation In Vivo

Activity-regulatedcytoskeleton-associated protein (Arc) protein is implicated as a master regulator of long-term forms of synaptic plasticity and memory formation, but the mechanisms controlling Arc protein function are little known. Post-translation modification by small ubiquitin-like modifier (SU...

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Bibliographic Details
Main Authors: Rajeevkumar R. Nair, Sudarshan Patil, Adrian Tiron, Tambudzai Kanhema, Debabrata Panja, Lars Schiro, Kamil Parobczak, Grzegorz Wilczynski, Clive R. Bramham
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Synaptic Neuroscience
Subjects:
actin cytoskeleton
brain-derived neurotrophic factor (BDNF)
dentate gyrus
hippocampus
immediate early protein
long-term potentiation (LTP)
Online Access:http://journal.frontiersin.org/article/10.3389/fnsyn.2017.00008/full

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