Quantitative membrane proteomics reveals new cellular targets of viral immune modulators.
Immunomodulators of pathogens frequently affect multiple cellular targets, thus preventing recognition by different immune cells. For instance, the K5 modulator of immune recognition (MIR2) from Kaposi sarcoma-associated herpesvirus prevents activation of cytotoxic T cells, natural killer cells, and...
Main Authors: | Eric Bartee, Ashley McCormack, Klaus Früh |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2006-10-01
|
Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC1626102?pdf=render |
Similar Items
-
Quantitative proteomics reveals cellular targets of celastrol.
by: Jakob Hansen, et al.
Published: (2011-01-01) -
Quantitative membrane proteomics reveals a role for tetraspanin enriched microdomains during entry of human cytomegalovirus.
by: Kasinath Viswanathan, et al.
Published: (2017-01-01) -
Quantitative Proteome Analysis of Atg5-Deficient Mouse Embryonic Fibroblasts Reveals the Range of the Autophagy-Modulated Basal Cellular Proteome
by: Kiran Bala Sharma, et al.
Published: (2019-11-01) -
Chimeric tumor modeling reveals role of partial PDL1 expression in resistance to virally induced immunotherapy
by: Mee Y. Bartee, et al.
Published: (2019-01-01) -
Modeling the measles paradox reveals the importance of cellular immunity in regulating viral clearance.
by: Sinead E Morris, et al.
Published: (2018-12-01)