Self-assembled filomicelles prepared from polylactide-poly(ethylene glycol) diblock copolymers for sustained delivery of cycloprotoberberine derivatives

Self-assembled filomicelles prepared from polylactide-poly(ethylene glycol) diblock copolymers for sustained delivery of cycloprotoberberine derivatives

Polylactide-poly(ethylene glycol) (PLA-PEG) block copolymers were synthesized by ring opening polymerization of l-lactide using a monomethoxy PEG (mPEG) as macroinitiator and zinc lactate as catalyst. The resulting diblock copolymers were characterized by 1H NMR and GPC. Polymeric micelles were prep...

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Bibliographic Details
Main Authors: Xue Liu, Yanxiang Wang, Peng Yun, Xin Shen, Feng Su, Yangsheng Chen, Suming Li, Danqing Song
Format: Article
Language:English
Published: Elsevier 2018-03-01
Series:Saudi Pharmaceutical Journal
Subjects:
Polymeric micelles
Filomicelles
PLA-PEG
A35
Drug delivery
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016418300082

Internet

http://www.sciencedirect.com/science/article/pii/S1319016418300082

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