Remaining challenges in cellular flavin cofactor homeostasis and flavoprotein biogenesis

Remaining challenges in cellular flavin cofactor homeostasis and flavoprotein biogenesis

The primary role of the water-soluble vitamin B2 (riboflavin) in cell biology is connected with its conversion into FMN and FAD, the cofactors of a large number of dehydrogenases, oxidases and reductases involved in energetic metabolism, epigenetics, protein folding, as well as in a number of divers...

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Bibliographic Details
Main Authors: Teresa Anna eGiancaspero, Matilde eColella, Carmen eBrizio, Graziana eDifonzo, Giuseppina Maria eFiorino, Piero eLeone, Roderich eBrandsch, Francesco eBonomi, Stefania eIametti, Maria eBarile
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-04-01
Series:Frontiers in Chemistry
Subjects:
Mitochondria
nucleus
FAD
Lysine specific demethylase 1
Flavinylation
Dimethylglycine dehydrogenase rat
Online Access:http://journal.frontiersin.org/Journal/10.3389/fchem.2015.00030/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fchem.2015.00030/full

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