Megalin dependent urinary cystatin C excretion in ischemic kidney injury in rats.

Megalin dependent urinary cystatin C excretion in ischemic kidney injury in rats.

Cystatin C, a marker of kidney injury, is freely filtered in the glomeruli and reabsorbed by the proximal tubules. Megalin and cubilin are endocytic receptors essential for reabsorption of most filtered proteins. This study examines the role of these receptors for the uptake and excretion of cystati...

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Bibliographic Details
Main Authors: Danny Jensen, Casper Kierulf-Lassen, Marie Louise Vindvad Kristensen, Rikke Nørregaard, Kathrin Weyer, Rikke Nielsen, Erik Ilsø Christensen, Henrik Birn
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5456377?pdf=render

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