Long Non-coding RNA MEG3 Promotes Pyroptosis in Testicular Ischemia-Reperfusion Injury by Targeting MiR-29a to Modulate PTEN Expression

Long Non-coding RNA MEG3 Promotes Pyroptosis in Testicular Ischemia-Reperfusion Injury by Targeting MiR-29a to Modulate PTEN Expression

Increasing evidence shows that the abnormal long non-coding RNAs (lncRNAs) expression is closely related to ischemia-reperfusion injury (I/R) progression. Studies have previously described that lncRNA MEG3 regulates pyroptosis in various organs I/R. Nevertheless, the related mechanisms of MEG3 in te...

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Bibliographic Details
Main Authors: Jin-zhuo Ning, Kai-xiang He, Fan Cheng, Wei Li, Wei-min Yu, Hao-yong Li, Ting Rao, Yuan Ruan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
testicular ischemia-reperfusion injury
MEG3
miR-29
PTEN
pyroptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.671613/full

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