ApoE mimetic peptide decreases Aβ production <it>in vitro </it>and <it>in vivo</it>

ApoE mimetic peptide decreases Aβ production <it>in vitro </it>and <it>in vivo</it>

<p>Abstract</p> <p>Background</p> <p>Apolipoprotein E (apoE) is postulated to affect brain Aβ levels through multiple mechanisms--by altering amyloid precursor protein (APP) processing, Aβ degradation, and Aβ clearance. We previously showed that an apoE-derived peptide...

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Main Authors: Pak Daniel TS, Turner R Scott, Dakshanamurthy Sivanesan, Davis Gary C, Babus Lenard W, Tesoriero Joseph A, Cirrito John R, Cordova Antoinette, Minami S Sakura, Rebeck G William, Paige Mikell, Hoe Hyang-Sook
Format: Article
Language:English
Published: BMC 2010-04-01
Series:Molecular Neurodegeneration
Online Access:http://www.molecularneurodegeneration.com/content/5/1/16

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