Febuxostat-Minoxidil Salt Solvates: Crystal Structures, Characterization, Interconversion and Solubility Performance

Febuxostat-Minoxidil Salt Solvates: Crystal Structures, Characterization, Interconversion and Solubility Performance

Three febuxostat-minoxidil salt solvates with acetone (ACE), tetrahydrofuran (THF) and isopropanol (IPA) are synthesized by solvent-assisted grinding and characterized by infrared (IR), nuclear magnetic resonance (1H-NMR), single crystal and powder X-ray diffraction (PXRD), thermogravimetry (TG) and...

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Bibliographic Details
Main Authors: Li-Yang Li, Rong-Kai Du, You-Li Du, Chun-Jing Zhang, Su Guan, Chang-Zhi Dong, Lei Zhang
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:Crystals
Subjects:
febuxostat
minoxidil
salt solvates
crystal structure
Online Access:http://www.mdpi.com/2073-4352/8/2/85

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