Tree-Based QSAR Model for Drug Repurposing in the Discovery of New Antibacterial Compounds Against <i>Escherichia coli</i>.

Tree-Based QSAR Model for Drug Repurposing in the Discovery of New Antibacterial Compounds Against <i>Escherichia coli</i>.

Drug repurposing appears as an increasing popular tool in the search of new treatment options against bacteria. In this paper, a tree-based classification method using Linear Discriminant Analysis (LDA) and discrete indexes was used to create a QSAR (Quantitative Structure-Activity Relationship) mod...

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Bibliographic Details
Main Authors: Beatriz Suay-Garcia, Antonio Falcó, J. Ignacio Bueso-Bordils, Gerardo M. Anton-Fos, M. Teresa Pérez-Gracia, Pedro A. Alemán-López
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Pharmaceuticals
Subjects:
drug repurposing
QSAR
antibiotics
drug development
Escherichia coli
Online Access:https://www.mdpi.com/1424-8247/13/12/431

Internet

https://www.mdpi.com/1424-8247/13/12/431

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