A Warburg-like metabolic program coordinates Wnt, AMPK, and mTOR signaling pathways in epileptogenesis.

Epilepsy is a complex neurological condition characterized by repeated spontaneous seizures and can be induced by initiating seizures known as status epilepticus (SE). Elaborating the critical molecular mechanisms following SE are central to understanding the establishment of chronic seizures. Here,...

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Bibliographic Details
Main Authors: Roaya S Alqurashi, Audrey S Yee, Taylor Malone, Sumaiah Alrubiaan, Mary W Tam, Kai Wang, Rozena R Nandedwalla, Wesley Field, Dalal Alkhelb, Katherine S Given, Raghib Siddiqui, James D Baleja, K Eric Paulson, Amy S Yee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0252282