THE RESTORATIVE COSMETIC CONSTITUENTS OF <i>Fragraea fragrans</i> FRUITS
This paper describes 3-hydroxyurs-12-en-28-oic acid and its structural isomer 3-hydroxyolean-12-en-28-oic acid isolated from Fragraea fragrans fruits and their biological activities; anti-tumor, anti-inflammation, anti-microbial, and anti-fungal included their ultra violet photo-protective effect af...
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doaj-cee928db65d2400b92895de6752af4fc2020-11-25T00:44:57ZengUniversitas Gadjah MadaIndonesian Journal of Chemistry1411-94202460-15782012-03-01121848810.22146/ijc.2137614474THE RESTORATIVE COSMETIC CONSTITUENTS OF <i>Fragraea fragrans</i> FRUITSDasril Basir0Julinar Julinar1Department of Chemistry, Faculty of Science, University of Sriwijaya, Palembang 30662, South SumatraDepartment of Chemistry, Faculty of Science, University of Sriwijaya, Palembang 30662, South SumatraThis paper describes 3-hydroxyurs-12-en-28-oic acid and its structural isomer 3-hydroxyolean-12-en-28-oic acid isolated from Fragraea fragrans fruits and their biological activities; anti-tumor, anti-inflammation, anti-microbial, and anti-fungal included their ultra violet photo-protective effect after exposed under sunlight radiation. They are useful for cosmetic ingredient. The above triterpenes are very promoting compounds for leukemia L1210 anti-tumor due to limited reports dealing with this type triterpenoid anti-tumor test. They significantly gave IC50 value of 5.78 µg/mL against leukemia L1210 cells, relatively closed to IC50 value of drugs, 4.0 µg/mL [12-13,17].https://jurnal.ugm.ac.id/ijc/article/view/21376Isomericursolic acidoleanolic acidFragraea fragranscosmetic |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Dasril Basir Julinar Julinar |
spellingShingle |
Dasril Basir Julinar Julinar THE RESTORATIVE COSMETIC CONSTITUENTS OF <i>Fragraea fragrans</i> FRUITS Indonesian Journal of Chemistry Isomeric ursolic acid oleanolic acid Fragraea fragrans cosmetic |
author_facet |
Dasril Basir Julinar Julinar |
author_sort |
Dasril Basir |
title |
THE RESTORATIVE COSMETIC CONSTITUENTS OF <i>Fragraea fragrans</i> FRUITS |
title_short |
THE RESTORATIVE COSMETIC CONSTITUENTS OF <i>Fragraea fragrans</i> FRUITS |
title_full |
THE RESTORATIVE COSMETIC CONSTITUENTS OF <i>Fragraea fragrans</i> FRUITS |
title_fullStr |
THE RESTORATIVE COSMETIC CONSTITUENTS OF <i>Fragraea fragrans</i> FRUITS |
title_full_unstemmed |
THE RESTORATIVE COSMETIC CONSTITUENTS OF <i>Fragraea fragrans</i> FRUITS |
title_sort |
restorative cosmetic constituents of <i>fragraea fragrans</i> fruits |
publisher |
Universitas Gadjah Mada |
series |
Indonesian Journal of Chemistry |
issn |
1411-9420 2460-1578 |
publishDate |
2012-03-01 |
description |
This paper describes 3-hydroxyurs-12-en-28-oic acid and its structural isomer 3-hydroxyolean-12-en-28-oic acid isolated from Fragraea fragrans fruits and their biological activities; anti-tumor, anti-inflammation, anti-microbial, and anti-fungal included their ultra violet photo-protective effect after exposed under sunlight radiation. They are useful for cosmetic ingredient. The above triterpenes are very promoting compounds for leukemia L1210 anti-tumor due to limited reports dealing with this type triterpenoid anti-tumor test. They significantly gave IC50 value of 5.78 µg/mL against leukemia L1210 cells, relatively closed to IC50 value of drugs, 4.0 µg/mL [12-13,17]. |
topic |
Isomeric ursolic acid oleanolic acid Fragraea fragrans cosmetic |
url |
https://jurnal.ugm.ac.id/ijc/article/view/21376 |
work_keys_str_mv |
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_version_ |
1716118522141081600 |