Prenatal exposure to valproic acid increases miR-132 levels in the mouse embryonic brain

Prenatal exposure to valproic acid increases miR-132 levels in the mouse embryonic brain

Abstract Background MicroRNAs, small non-coding RNAs, are highly expressed in the mammalian brain, and the dysregulation of microRNA levels may be involved in neurodevelopmental disorders such as autism spectrum disorder (ASD). In the present study, we examined whether prenatal valproic acid (VPA) e...

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Bibliographic Details
Main Authors: Yuta Hara, Yukio Ago, Erika Takano, Shigeru Hasebe, Takanobu Nakazawa, Hitoshi Hashimoto, Toshio Matsuda, Kazuhiro Takuma
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Molecular Autism
Subjects:
Autism mouse model
Valproic acid
MicroRNA
Embryonic brain
Online Access:http://link.springer.com/article/10.1186/s13229-017-0149-5

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