ITE and TCDD differentially regulate the vascular remodeling of rat placenta via the activation of AhR.

Vascular remodeling in the placenta is essential for normal fetal development. The previous studies have demonstrated that in utero exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD, an environmental toxicant) induces the intrauterine fetal death in many species via the activation of aryl hydroc...

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Bibliographic Details
Main Authors: Yanming Wu, Xiao Chen, Qian Zhou, Qizhi He, Jiuhong Kang, Jing Zheng, Kai Wang, Tao Duan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3901702?pdf=render