Direct rosiglitazone action on steroidogenesis and proinflammatory factor production in human granulosa-lutein cells

<p>Abstract</p> <p>Background</p> <p>Ovarian granulosa cells are the predominant source of estradiol and progesterone biosynthesis in vivo. Rosiglitazone, a synthetic agonist of the peroxisome proliferator-activated receptor gamma (PPAR gamma), is applied as the treatme...

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Bibliographic Details
Main Authors: Wang Yongwei, Wang Jian, Cheng Linan, Chen Junling, Sun Xiaoxi, Chen Qiuju, Sun Zhaogui
Format: Article
Language:English
Published: BMC 2009-12-01
Series:Reproductive Biology and Endocrinology
Online Access:http://www.rbej.com/content/7/1/147